HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cycloheptylamine → HCID 86729816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cycloheptylamine | HCID 2899 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 1325307-27-4 | HCID 53335886 | — |
| Reactant | 3,7-Diphenylthieno[3,2-d]pyrimidin-4(3H)-one | HCID 78324865 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 86729816 | HCID 86729816 | 47% |
Reaction Steps
In the same manner as the synthesis of Compound 1, methyl 3-amino-4-(2-fluorophenyl)thiophene-2-carboxylate (70 mg, 0.28 mmol), triethyl orthoformate (2 ml), cycloheptylamine (0.066 ml, 0.52 mmol), and acetic acid (0.1 ml) were used to give 45 mg (0.13 mmol, 47% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260448B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-cb8f6e9bc33f49e8a423043a079c1c30 |
| Source note | uspto-grants-2016_02 |