HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118415268, compound → HCID 118415250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118415268 | HCID 118415268 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 118415250 | HCID 118415250 | 33.7% |
Reaction Steps
(3R,4S)-tert-butyl4-(benzyl(methyl)amino)-4-cyclopentyl-3-methoxybutanoate (8) (3.0 g, 8.3 mmol) in ethanol (30 mL) was hydrogenated with Pd/C (1.3 g) for overnight. After the removal of residual Pd/C by filtration, the filtrate was concentrated to afford the desired product 9 (760 mg, 33.6.0%). LC-MS: m/z 272.1[M+H+]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09260478B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-0f9780bd55a34a00b8e621b0b33d3092 |
| Source note | uspto-grants-2016_02 |