(4,4-Dimethoxybutyl)(methyl)amine → 2-(5-chloro-1-(2-(2-methylpyrimidin-5-yl)ethyl)-1H-indol-3-yl)-N-methylethanamine

HRID 1775895Notes

Reaction equation

HRID 1775895 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH2:10][CH2:11][C:12]2[CH:13]=[N:14][C:15]([CH3:18])=[N:16][CH:17]=2)N)=[CH:4][CH:3]=1.CO[CH:21](OC)[CH2:22][CH2:23][CH2:24][NH:25][CH3:26]>>[Cl:1][C:2]1[CH:7]=[C:6]2[C:5](=[CH:4][CH:3]=1)[N:8]([CH2:10][CH2:11][C:12]1[CH:13]=[N:14][C:15]([CH3:18])=[N:16][CH:17]=1)[CH:21]=[C:22]2[CH2:23][CH2:24][NH:25][CH3:26]

Participants

3

Reactant 2

HCID 22563572(4,4-Dimethoxybutyl)(methyl)amineHCID 669116201-(4-Chlorophenyl)-1-(2-(2-methylpyrimidin-5-yl)ethyl)hydrazine

Product 1

HCID 669117812-(5-chloro-1-(2-(2-methylpyrimidin-5-yl)ethyl)-1H-indol-3-yl)-N-methylethanamine

Procedure

The title compound is prepared by General Method 3 using 1-(4-chlorophenyl)-1-(2-(2-methylpyrimidin-5-yl)ethyl)hydrazine and 4,4-dimethoxy-N-methylbutan-1-amine.

Sources & evidence

ORD record
ord-456084990b3d460eb01c65910689b91a
Source dataset
uspto-grants-2016_02
Patent number
US09260429B2

Reaction notes

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