5-Oxotetrahydro-2-furancarbonyl chloride → 4'-Methoxy-2-(5-oxotetrahydrofuran-2-carbonyl)aminobenzophenone

HRID 1776Notes

Reaction equation

HRID 1776 reaction equation
[NH2:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][CH:7]=1)=[O:5].[O:18]=[C:19]1[O:23][CH:22]([C:24](Cl)=[O:25])[CH2:21][CH2:20]1>>[CH3:13][O:12][C:9]1[CH:10]=[CH:11][C:6]([C:4](=[O:5])[C:3]2[CH:14]=[CH:15][CH:16]=[CH:17][C:2]=2[NH:1][C:24]([CH:22]2[CH2:21][CH2:20][C:19](=[O:18])[O:23]2)=[O:25])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 108445405-Oxotetrahydro-2-furancarbonyl chlorideHCID 122064592-Amino-4'-methoxybenzophenone

Product 1

HCID 541935034'-Methoxy-2-(5-oxotetrahydrofuran-2-carbonyl)aminobenzophenone

Procedure

In substantially the same manner as in Example 8 (1), 8 g of 2-amino-4'-methoxybenzophenone was allowed to react with 5-oxotetrahydrofuran-2-carbonyl chloride to give 12 g of 4'-methoxy-2-(5-oxotetrahydrofuran-2-carbonyl)aminobenzophenone as an oily product.

Sources & evidence

ORD record
ord-9e9ed99cddf843adaf7a03857e42c160
Source dataset
uspto-grants-1998_03
Patent number
US05726306

Reaction notes

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