HCID 86679412, compound → HCID 86679413, compound

Participants

Reaction Steps

(S)-4-(2-(2-(tert-butoxycarbonylamino)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide (80 mg, 0.17 mmol) was dissolved in HCl 4M in EtOAc (2 ml) and stirred at RT for 3 hours. The solvent was evaporated under vacuum, and the crude product was crystallized from EtOAc/Hexane to give 60 mg of the desired product (Yield: 69%).

Provenance & Evidence