Hydrochloric Acid → HCID 86679429, compound

Participants

Reaction Steps

tert-Butyl 4-methoxy-3-(N-(2-morpholinoethyl)methylsulfonamido)benzyl-(methyl)carbamate (114 mg, 0.249 mmol) was dissolved in dry DCM (6 ml), and HCl 4M in dioxane (500 μl, 2.000 mmol) was added. The reaction was stirred at RT for 24 hours. The solvent was evaporated under vacuum and N-(2-methoxy-5-((methylamino)methyl)phenyl)-N-(2-morpholinoethyl)methanesulfonamide was obtained as hydrochloride salt (89 mg, 0.249 mmol, 100% yield, MS/ESI+ 358.1 [MH]+) that was used in the next step without further purification.

Provenance & Evidence