反应详情

Benzyl 3-(3,4-dimethoxyphenylamino)-3-oxopropanoate (200 mg, 0.607 mmol) was dissolved in MeOH, and then Pd/C 5% (129 mg, 0.061 mmol) was added. The solution was shaken under hydrogen atmosphere at 30 psi on a Parr apparatus for 30 minutes. The catalyst was filtered off, and the solvent removed under vacuum to give 3-(3,4-dimethoxyphenylamino)-3-oxopropanoic acid (120 mg, 83% yield).

1. filtrationThe catalyst was filtered off
2. customthe solvent removed under vacuum