HCID 89455858, compound → HCID 89459942, compound

Participants

Reaction Steps

To a solution of 2-(benzyloxy)-2-oxoethyl 3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoate (0.508 g, 1.029 mmol) in MeOH (30 m) and EtOAc (3 ml), 10% w/w Pd/C (a catalytic amount) was added, and the mixture was hydrogenated in a Parr apparatus at 20 psi for 3 hours. The catalyst was filtered off and the filtrate was evaporated to dryness affording 2-(3-(N-(tert-butoxycarbonyl)methyl-sulfonamido)-4-methoxybenzoyloxy)acetic acid (0.387 g, 0.959 mmol, 93% yield, MS/ESI+not detectable [MH]+). This product was used without any further purification.

Provenance & Evidence