HCID 86679499, compound → HCID 86679500, compound

Participants

Reaction Steps

2-(benzyloxy)-2-oxoethyl 3-(N-(2-amino-2-oxoethyl)methylsulfonamido)-4-methoxybenzoate (180 mg, 0.400 mmol) was dissolved in MeOH (10 ml), then Pd/C 5% (85 mg, 0.040 mmol) was added. The solution was shaken under hydrogen atmosphere at 35 psi on a Parr apparatus for 30 minutes. The catalyst was filtered off, and the solvent removed under vacuum to give 2-(3-(N-(2-amino-2-oxoethyl)methylsulfonamido)-4-methoxybenzoyloxy)acetic acid (130 mg, 90% yield).

Provenance & Evidence