Potassium Carbonate → HCID 86679504, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 2-(4-hydroxy-3-nitrophenyl)acetate (1.0 g, 4.74 mmol) in CH3CN (10 ml), K2CO3 (0.327 g, 2.37 mmol) and (bromomethyl)cyclopropane (0.460 ml, 4.74 mmol) were added and the mixture was heated under MW irradiation at 100° C. for 1 hour. The insoluble inorganic salts were filtered off and the filtrate was evaporated to dryness to give crude methyl 2-(4-(cyclopropylmethoxy)-3-nitrophenyl)acetate (1.3 g, yield considered to be quantitative, MS/ESI+265.9 [MH]+). This crude was used without any additional purification.

Provenance & Evidence