HCID 86679520, compound → HCID 86679521, compound

Participants

Reaction Steps

A mixture of 2-(benzyloxy)-2-oxoethyl 4-(cyclopropylmethoxy)-3-(methylsulfonyloxy)benzoate (0.238 g, 0.548 mmol) and 10% w/w Pd/C (0.030 g, 0.028 mmol) in MeOH (17 ml) and EtOAc (3 ml) was hydrogenated at 20 psi for 2 hours. The catalyst was filtered off, and the solvent was removed under vacuum affording 2-(4-(cyclopropylmethoxy)-3-(methylsulfonyloxy)benzoyloxy)acetic acid (0.178 g, 0.517 mmol, 94% yield, MS/ESI+ 344.9 [MH]+). The product was used without any further purification.

Provenance & Evidence