HRID1776712

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12851675

未命名化合物

结构：Nc1cc(OCc2ccc3ccccc3n2)ccc1NCc1cccc(Br)c1

HCID90414557

未命名化合物

结构：CCOC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Br)cc2)CCCC1

HCID90414649

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1C(c2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(Br)c2)C1(C)C

HCID90416020

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using similar methods to those for ethyl 1-((1-(4-bromobenzyl)-5-(quinolin-2-ylmethoxy)-1H-benzo[d]imidazol-2-yl)methyl)cyclopentanecarboxylate using N1-(3-bromobenzyl)-4-(quinolin-2-ylmethoxy)benzene-1,2-diamine and cis-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexane-2,4-dione. MS (ESI): mass calcd. for C32H30BrN3O3, 583.15; m/z found, 584.1 [M+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2bb0d129b47143b98669ca1037bdc3c8
来源数据集: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09265770B2
来源说明: uspto-grants-2016_02

反应 SMILES

BrC1C=CC([CH2:6][N:7]2[C:11]3[CH:12]=[CH:13][C:14]([O:16][CH2:17][C:18]4[CH:27]=[CH:26][C:25]5[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=5)[N:19]=4)=[CH:15][C:10]=3[N:9]=[C:8]2[CH2:28][C:29]2([C:34]([O:36][CH2:37][CH3:38])=[O:35])CC[CH2:31][CH2:30]2)=CC=1.[Br:41][C:42]1[CH:43]=[C:44]([CH:66]=[CH:67][CH:68]=1)CNC1C(N)=CC(OCC2C=CC3C(=CC=CC=3)N=2)=CC=1.[CH3:69]C1(C)[C@@H]2[C@H]1C(=O)OC2=O>>[Br:41][C:42]1[CH:68]=[C:67]([CH:66]=[CH:44][CH:43]=1)[CH2:6][N:7]1[C:11]2[CH:12]=[CH:13][C:14]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[N:19]=3)=[CH:15][C:10]=2[N:9]=[C:8]1[CH:28]1[CH:29]([C:34]([O:36][CH2:37][CH3:38])=[O:35])[C:30]1([CH3:31])[CH3:69]