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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1776912Generated: October 25, 2026

5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-2-(4-fluorophenyl)-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide → HCID 178464693, compound

https://huagongshe.com/reaction/1776912

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-2-(4-fluorophenyl)-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamideHCID 86728290—
SolventDMA dimethylacetamideHCID 19097097—
ProductHCID 178464693HCID 178464693—

Reaction Steps

To a solution of 5-(11-fluoro-6H-pyrido[2′,3′:5,6][1,3]oxazino[3,4-a]indol-2-yl)-2-(4-fluorophenyl)-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide (100 mg, 0.17 mmol) in DMA-DMA (2 mL) was stirred at 120° C. for 2 hour. The reaction mixture was concentrated in vacuo and the resulting residue was used to the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09265773B2
Source datasetuspto-grants-2016_02
ORD IDord-7a6b57e5fa0143a58a6302e47794454f
Source noteuspto-grants-2016_02