Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Hydroxybenzamide | HCID 342403 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 354312 | HCID 354312 | — |
Reaction Steps
To a stirred mixture of 3-hydroxybenzamide (300 mg, 2.19 mmol) in MeCN (5 mL) was added ethyl bromoacetate (545 mg, 3.29 mmol) and K2CO3 (907 mg, 6.57 mmol). The mixture was stirred at 80° C. for 4 hours. The mixture was filtered and the filtrate concentrated. The residue was directly for the next step. LCMS (m/z): 224.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09266836B2 |
|---|
| Source dataset | uspto-grants-2016_02 |
|---|
| ORD ID | ord-2ac1b2a8e12149bd8c0aa77bdfdbf9e6 |
|---|
| Source note | uspto-grants-2016_02 |
|---|
