Acetic Anhydride → 2-methyl-5-nitro-4H-benzo[d][1,3]oxazin-4-one

Participants

Reaction Steps

In certain embodiments, step (a) (i.e., reacting 2-amino-6-nitrobenzoic acid with acetic anhydride in a solvent to form 2-methyl-5-nitro-4H-benzo[d][1,3]oxazin-4-one) is conducted at a temperature ranging from about 50 to about 150° C., from about 75 to about 120° C., from about 75 to about 100° C., from about 80 to about 100° C., from about 80 to about 95° C., or from about 85 to about 90° C. In certain embodiments, step (a) is conducted at a temperature from about 85 to about 90° C.

Provenance & Evidence