Ethanolamine → HCID 178424652, compound

HRID 1777327Notes

Reaction equation

HRID 1777327 reaction equation
[C:1]([C:4]1[N:9]=[C:8]([C:10]2[CH2:15][CH2:14][C:13]([CH3:17])([CH3:16])[CH2:12][CH:11]=2)[C:7]([NH:18][C:19]([C:21]2[NH:22][C:23]([C:26]#[N:27])=[CH:24][N:25]=2)=[O:20])=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[NH2:28][CH2:29][CH2:30]O>>[CH3:16][C:13]1([CH3:17])[CH2:14][CH2:15][C:10]([C:8]2[C:7]([NH:18][C:19]([C:21]3[NH:25][CH:24]=[C:23]([C:26]#[N:27])[N:22]=3)=[O:20])=[CH:6][CH:5]=[C:4]([C:1]3([CH3:2])[NH:28][CH2:29][CH2:30][O:3]3)[N:9]=2)=[CH:11][CH2:12]1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 59457538HCID 59457538, compound

Product 1

HCID 178424652HCID 178424652, compound

Procedure

The title compound is prepared from 5-cyano-1H-imidazole-2-carboxylic acid [6-acetyl-2-(4,4-dimethyl-cyclohex-1-enyl)-pyridin-3-yl]-amide (as prepared in the previous step) and 2-aminoethanol according to the procedure in Example 1, step (h).

Sources & evidence

ORD record
ord-2fa9e66b78974eca8414cb674dd911ae
Source dataset
uspto-grants-2016_02
Patent number
US09266866B2

Reaction notes

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