HCID 67991756, compound → HCID 118020682, compound

Participants

Reaction Steps

By using (2RS,5SR)-[2-(chloromethyl)-5-methyl-1,3-oxazinan-3-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone obtained in Reference Example 35 (0.52 g, 1.5 mmol) and 5-fluoro-2-(1H-pyrazol-4-yl)pyridine obtained in Reference Example 11 (0.23 g, 1.4 mmol), the same procedure as in Example 48 was carried out to obtain the title compound (0.44 g). The obtained racemic mixture (0.070 g) was divided using a semi-preparative column based on the racemic compound analysis condition described earlier (condition 13, Rt1=6.6 min, Rt2=12.4 min) to obtain the title compound (0.030 g) having a short relative retention time (Rt1=6.6 min) (colorless oil).

Provenance & Evidence