HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777559Generated: October 26, 2026
Sodium Azide → (4-Azidobut-1-ynyl)triethylsilane
https://huagongshe.com/reaction/1777559
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 4-(Triethylsilyl)but-3-yn-1-yl 4-methylbenzene-1-sulfonate | HCID 12030138 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (4-Azidobut-1-ynyl)triethylsilane | HCID 86663839 | 103.6% |
Reaction Steps
Sodium azide (1.80 g; 27.65 mmol) was added to a solution of 4-(triethylsilyl)but-3-ynyl 4-methylbenzenesulfonate (3.12 g; 9.22 mmol) in DMF (15 mL) and stirred at 60° C. for 3 hours. After cooling, the volatiles were removed under reduced pressure and the residue was partitioned between saturated ammonium chloride and ethyl acetate. The organic layer was dried and concentrated under reduced pressure to afford 2.0 g (quantitative yield) of the desired compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09266832B2 |
|---|
| Source dataset | uspto-grants-2016_02 |
|---|
| ORD ID | ord-4a127a6e1dfe43e2ab455f8dd65f5b28 |
|---|
| Source note | uspto-grants-2016_02 |
|---|
