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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777568Generated: November 2, 2026

Pyridine → Methyl 4-phenoxybenzoate

https://huagongshe.com/reaction/1777568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantMethylparabenHCID 7456—
ReactantPhenylboronic AcidHCID 66827—
CatalystCupric acetateHCID 8895—
SolventDichloromethaneHCID 6344—
ProductMethyl 4-phenoxybenzoateHCID 607605—

Reaction Steps

A mixture of methyl 4-hydroxybenzoate (0.200 g; 1.31 mmol), benzeneboronic acid (0.321 g; 2.63 mmol), copper acetate (0.477 g; 2.63 mmol) and pyridine (0.213 mL; 2.63 mmol) in dichloromethane (8 mL) was stirred at room temperature overnight. The reaction mixture was filtered and concentrated in vacuo.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266832B2
Source datasetuspto-grants-2016_02
ORD IDord-9ad4b59d447d4442bef54052f43b1b44
Source noteuspto-grants-2016_02