Pyrazole → HCID 67974590, compound

Participants

Reaction Steps

4-((1H-Pyrazol-1-yl)methyl)-N-(2-(5-Chloro-1H-indol-3-yl)ethyl)benzamide was prepared following Method C starting from N-(2-(5-chloro-1H-indol-3-yl)ethyl)-4-(chloromethyl)benzamide (0.069 g; 0.199 mmol), pyrazole (0.062 g; 0.893 mmol) and sodium iodide (0.150 g; 0.994 mmol) in THF (3 mL), under a microwave irradiation at 150° C. for 20 minutes. Flash chromatography on silica gel (eluent 7 to 60% ethyl acetate in dichloromethane) furnished 0.064 g (85%) of the title compound as a white solid.

Provenance & Evidence