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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777682Generated: October 31, 2026

HCID 86699394, compound → HCID 67974428, compound

https://huagongshe.com/reaction/1777682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86699394HCID 86699394—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 67974428HCID 6797442830%

Reaction Steps

N-(2-(5-Cyano-2-(triethylsilyl)-1H-indol-3-yl)ethyl)-4-(3-fluorobenzyl)benzamide (0.056 g; 0.109 mmol) was dissolved in trifluoroacetic acid (3 mL) and stirred at room temperature for 3 hours. The solution was concentrated under reduced pressure and the crude material was purified by flash chromatography on silica gel (eluent 20 to 100% ethyl acetate in heptane) to afford 0.013 g (29%) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266832B2
Source datasetuspto-grants-2016_02
ORD IDord-44213f7d66bd481889016c6ae404f72e
Source noteuspto-grants-2016_02