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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777683Generated: October 31, 2026

HCID 86699395, compound → HCID 67974647, compound

https://huagongshe.com/reaction/1777683

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86699395HCID 86699395—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 67974647HCID 6797464758%

Reaction Steps

N-(2-(5-Acetyl-2-(triethylsilyl)-1H-indol-3-yl)ethyl)-4-(3-fluorobenzyl)benzamide (0.043 g; 0.109 mmol) was dissolved in trifluoroacetic acid (3 mL) and stirred at room temperature for 3 hours. The solution was concentrated under reduced pressure and the crude material was purified by flash chromatography on silica gel (eluent 20 to 100% ethyl acetate in heptane) to afford 0.020 g (58%) of the title compound as a yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266832B2
Source datasetuspto-grants-2016_02
ORD IDord-4594990c79cc4f07a39dcaa530b27fc2
Source noteuspto-grants-2016_02