HCID 89726588, compound → HCID 89725903, compound

HRID 1777747Notes

Reaction equation

HRID 1777747 reaction equation
C([O:8][C:9](=[O:21])[CH2:10][N:11]1[C:19]2[CH2:18][CH2:17][N:16]([CH3:20])[CH2:15][C:14]=2[N:13]=[CH:12]1)C1C=CC=CC=1>CCO>[CH3:20][N:16]1[CH2:17][CH2:18][C:19]2[N:11]([CH2:10][C:9]([OH:21])=[O:8])[CH:12]=[N:13][C:14]=2[CH2:15]1

Participants

3

Reactant 1

HCID 89726588HCID 89726588, compound

Product 1

HCID 89725903HCID 89725903, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The final compound was prepared using a method analogous to that of Example 14 step 14.2, (5-methyl-4,5,6,7-tetrahydro-imidazo[4,5-c]pyridin-1-yl)acetic acid benzyl ester replacing intermediate 14.1 and using EtOH instead of MeOH/AcOH. LC-MS (B): tR=0.13 min; [M+H]+: 196.31.

Sources & evidence

ORD record
ord-91cc6cb946db4d1695fa1b5c40cb0475
Source dataset
uspto-grants-2016_02
Patent number
US09266876B2

Reaction notes

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