HCID 89725972, compound → HCID 82512074, compound

HRID 1777750Notes

Reaction equation

HRID 1777750 reaction equation
C([O:8][C:9](=[O:17])[CH2:10][N:11]1[C:15]([CH3:16])=[N:14][CH:13]=[N:12]1)C1C=CC=CC=1>CCO>[CH3:16][C:15]1[N:11]([CH2:10][C:9]([OH:17])=[O:8])[N:12]=[CH:13][N:14]=1

Participants

3

Reactant 1

HCID 89725972HCID 89725972, compound

Product 1

HCID 82512074HCID 82512074, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The final compound (5-methyl-[1,2,4]triazol-1-yl)-acetic acid was prepared using a method analogous to that of Example 14 step 14.2, (5-methyl-[1,2,4]triazol-1-yl)-acetic acid benzyl ester replacing intermediate 14.1 and using EtOH instead of MeOH/AcOH. LC-MS (B): tR=0.19 min; [M+H]+: 142.24.

Sources & evidence

ORD record
ord-18488ccd45734b569b2f957a34b2f0d0
Source dataset
uspto-grants-2016_02
Patent number
US09266876B2

Reaction notes

Loading…