HCID 89726365, compound → HCID 89726306, compound

HRID 1777755Notes

Reaction equation

HRID 1777755 reaction equation
[CH2:1]([O:8][C:9](=[O:21])[CH2:10][N:11]1[CH:20]=[C:14]2[CH2:15][N:16]([CH3:19])[CH2:17][CH2:18][C:13]2=[N:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO>[CH2:1]([O:8][C:9](=[O:21])[CH2:10][N:11]1[C:20]2[CH2:14][CH2:15][N:16]([CH3:19])[CH2:17][C:18]=2[CH:13]=[N:12]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 89726365HCID 89726365, compound

Product 1

HCID 89726306HCID 89726306, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The final compound was prepared using a method analogous to that of Example 14 step 14.2, (5-methyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-2-yl)-acetic acid benzyl ester replacing intermediate 14.1 and using MeOH instead of MeOH/AcOH. LC-MS (B): tR=0.17 min; [M+H]+: 196.29.

Sources & evidence

ORD record
ord-f67a440813f1486a9a501434b71a5c8e
Source dataset
uspto-grants-2016_02
Patent number
US09266876B2

Reaction notes

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