HCID 89726086, compound → HCID 89726358, compound

HRID 1777760Notes

Reaction equation

HRID 1777760 reaction equation
C([O:8][C:9](=[O:21])[CH2:10][N:11]1[C:15]([CH3:16])=[N:14][C:13]([CH2:17][N:18]([CH3:20])[CH3:19])=[N:12]1)C1C=CC=CC=1>CCO>[CH3:19][N:18]([CH2:17][C:13]1[N:14]=[C:15]([CH3:16])[N:11]([CH2:10][C:9]([OH:21])=[O:8])[N:12]=1)[CH3:20]

Participants

3

Reactant 1

HCID 89726086HCID 89726086, compound

Product 1

HCID 89726358HCID 89726358, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The final compound was prepared using a method analogous to that of Example 14 step 14.2, (3-dimethylaminomethyl-5-methyl-[1,2,4]triazol-1-yl)-acetic acid benzyl ester replacing intermediate 14.1 and using EtOH instead of MeOH/AcOH. LC-MS (B): tR=0.15 min; [M+H]+: 199.16.

Sources & evidence

ORD record
ord-feb4e6a888704901ac94529b35323ba0
Source dataset
uspto-grants-2016_02
Patent number
US09266876B2

Reaction notes

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