HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(2-(1-((tert-Butoxycarbonyl)amino)-2-methylpropyl)-5-chloropyridin-3-yl)methyl methanesulfonate → 1-(2-((S)-1-((tert-butoxycarbonyl)amino)-2-methylpropyl)-5-chloropyridin-3-yl)ethyl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(2-(1-((tert-Butoxycarbonyl)amino)-2-methylpropyl)-5-chloropyridin-3-yl)methyl methanesulfonate | HCID 118274937 | — |
| Reactant | tert-butyl((1S)-1-(5-chloro-3-(1-hydroxyethyl)pyridin-2-yl)-2-methylpropyl)carbamate | HCID 118282594 | — |
| Product | 1-(2-((S)-1-((tert-butoxycarbonyl)amino)-2-methylpropyl)-5-chloropyridin-3-yl)ethyl methanesulfonate | HCID 118274916 | — |
Reaction Steps
Procedure same as that for (S)-(2-(1-((tert-butoxycarbonyl)amino)-2-methylpropyl)-5-chloropyridin-3-yl)methyl methanesulfonate, using tert-butyl((1S)-1-(5-chloro-3-(1-hydroxyethyl)pyridin-2-yl)-2-methylpropyl)carbamate as a starting material. LC-MS tR=1.03 min in 1 min chromatography, MS (ESI) m/z 407.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266886B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-d6f5eaa85ab34ba8a89379d0d3359032 |
| Source note | uspto-grants-2016_02 |