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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1777890Generated: November 1, 2026

6-Amino-4-chloro-3-pyridinecarbonitrile → HCID 118036729, compound

https://huagongshe.com/reaction/1777890

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Amino-4-chloro-3-pyridinecarbonitrileHCID 21949219—
Reactanttert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylateHCID 34178604—
ProductHCID 118036729HCID 118036729—

Reaction Steps

From intermediate 16 and tert-butyl 2,8-diazaspiro[4.5]decane-2-carboxylate, reacted in an analogous manner to the preparation of intermediate 42. 1H NMR (400 MHz, DMSO-d6) δ 8.06 (s, 1H), 6.66 (s, 2H), 5.90 (s, 1H), 3.10-3.32 (s, 8H), 1.69-1.79 (m, 2H), 1.52-1.66 (m, 4H), 1.40 (s, 9H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266883B2
Source datasetuspto-grants-2016_02
ORD IDord-95f7328154564306bac9fb6998a40dea
Source noteuspto-grants-2016_02