2-Fluoroethylamine → HCID 118036303, compound

HRID 1777946Notes

Reaction equation

[NH2:1][C:2]1[CH:9]=[C:8](F)[C:5]([C:6]#[N:7])=[CH:4][N:3]=1.[F:11][CH2:12][CH2:13][NH2:14]>>[NH2:1][C:2]1[CH:9]=[C:8]([NH:14][CH2:13][CH2:12][F:11])[C:5]([C:6]#[N:7])=[CH:4][N:3]=1

Participants

Reactant 2

HCID 99962-Fluoroethylamine

HCID 1180369016-Amino-4-fluoronicotinonitrile

Product 1

HCID 118036303HCID 118036303, compound

Procedure

From intermediate 21 and 2-fluoroethanamine, reacted in an analogous manner to the preparation of intermediate 88. (UPLC-MS 6) tR 0.49; ESI-MS 181.1 [M+H]+.

Sources & evidence

ORD record: ord-ab04e9aa4a4b4064a4661e9052c47a96
Source dataset: uspto-grants-2016_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09266883B2

Reaction notes

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