2-Amino-5-cyanopyridine → Phenyl (5-cyanopyridin-2-yl)carbamate

HRID 1778019Notes

Reaction equation

HRID 1778019 reaction equation
NC1C=CC(C#N)=CN=1.[C:10]1([O:16][C:17](=[O:32])[NH:18][C:19]2[CH:24]=[C:23](OCCOC)[C:22]([C:30]#[N:31])=[CH:21][N:20]=2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:10]1([O:16][C:17](=[O:32])[NH:18][C:19]2[CH:24]=[CH:23][C:22]([C:30]#[N:31])=[CH:21][N:20]=2)[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 8182602-Amino-5-cyanopyridineHCID 125470569Phenyl (5-cyano-4-(2-methoxyethoxy)pyridin-2-yl)carbamate

Product 1

HCID 57469773Phenyl (5-cyanopyridin-2-yl)carbamate

Procedure

From 2-amino-5-cyanopyridine, reacted in an analogous manner to the preparation of intermediate 108. (UPLC-MS 6) tR 0.92; ESI-MS 240.1 [M+H]+.

Sources & evidence

ORD record
ord-7c1bceba99d94614a9c13100d9243a4d
Source dataset
uspto-grants-2016_02
Patent number
US09266883B2

Reaction notes

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