HCID 118036529, compound → HCID 118036448, compound

HRID 1778102Notes

Reaction equation

HRID 1778102 reaction equation
[C:1]([C:3]1[C:4]([NH:35][CH2:36][CH2:37][O:38][CH3:39])=[CH:5][C:6]([NH:9][C:10]([N:12]2[C:21]3[C:16](=[CH:17][C:18]([CH2:27][N:28]4[CH2:33][CH2:32][S:31][CH2:30][C:29]4=[O:34])=[C:19]([CH:22](OC)[O:23]C)[N:20]=3)[CH2:15][CH2:14][CH2:13]2)=[O:11])=[N:7][CH:8]=1)#[N:2]>C(Cl)Cl>[C:1]([C:3]1[C:4]([NH:35][CH2:36][CH2:37][O:38][CH3:39])=[CH:5][C:6]([NH:9][C:10]([N:12]2[C:21]3[C:16](=[CH:17][C:18]([CH2:27][N:28]4[CH2:33][CH2:32][S:31][CH2:30][C:29]4=[O:34])=[C:19]([CH:22]=[O:23])[N:20]=3)[CH2:15][CH2:14][CH2:13]2)=[O:11])=[N:7][CH:8]=1)#[N:2]

Participants

3

Reactant 1

HCID 118036529HCID 118036529, compound

Product 1

HCID 118036448HCID 118036448, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

From intermediate 207, reacted in an analogous manner to the preparation of Example 92. The crude material was dissolved in DCM and Et2O and precipitated by slow evaporation of solvents. The resulting solid was filtered and dried to yield the title compound as a pink solid.

Workup

  1. customEt2O and precipitated by slow evaporation of solvents
  2. filtrationThe resulting solid was filtered
  3. customdried

Sources & evidence

ORD record
ord-06be40126e6046fb858bb49b947c61f9
Source dataset
uspto-grants-2016_02
Patent number
US09266883B2

Reaction notes

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