3-Methylbenzoic acid → HCID 118130050, compound

HRID 1778130Notes

Reaction equation

HRID 1778130 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[CH:11]=[N:12][CH:13]=[C:14]([CH:19]=2)[C:15]([O:17][CH3:18])=[O:16])[CH:5]=[CH:6][CH:7]=1.[CH3:20][C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][CH:29]=1)[C:24](O)=[O:25]>>[CH3:20][C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][CH:29]=1)[C:24]([NH:1][C:2]1[CH:3]=[C:4]([C:8]#[C:9][C:10]2[CH:11]=[N:12][CH:13]=[C:14]([CH:19]=2)[C:15]([O:17][CH3:18])=[O:16])[CH:5]=[CH:6][CH:7]=1)=[O:25]

Participants

3

Reactant 2

HCID 74183-Methylbenzoic acidHCID 118130124HCID 118130124, compound

Product 1

HCID 118130050HCID 118130050, compound

Procedure

In a manner similar to that described in Example 1, methyl 5-((3-aminophenyl)ethynyl)nicotinate and 3-methylbenzoic acid are converted to the title compound.

Sources & evidence

ORD record
ord-92a27f15f3b8416abf363402391b6ed3
Source dataset
uspto-grants-2016_02
Patent number
US09266869B2

Reaction notes

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