HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbenzoic acid → Methyl 5-(N-{[6-amino-5-({3-[(3-methylbenzoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-methylsulfonimidoyl)pentanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbenzoic acid | HCID 7418 | — |
| Reactant | Methyl 5-[N-({6-amino-5-[(3-aminophenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]pentanoate | HCID 118130063 | — |
| Product | Methyl 5-(N-{[6-amino-5-({3-[(3-methylbenzoyl)amino]phenyl}ethynyl)pyridin-3-yl]carbonyl}-S-methylsulfonimidoyl)pentanoate | HCID 91809241 | — |
Reaction Steps
In a manner similar to that described in Example 25, methyl 5-[N-({6-amino-5-[(3-aminophenyl)ethynyl]pyridin-3-yl}carbonyl)-S-methylsulfonimidoyl]pentanoate and 3-methylbenzoic acid were coupled to give the title compound as a white foam (82 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266869B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-9821035b9b0e456e984f0c43f8296ad3 |
| Source note | uspto-grants-2016_02 |