Methyl 3-(2-acetylfuran-3-yl)-6-benzenesulfonylmethyl-2-hydroxybenzoate → Methyl 6-(benzenesulfonylmethyl)-2-hydroxy-3-[2-(1-hydroxyethyl)-furan-3-yl]-benzoate

HRID 1778348Notes

Reaction equation

HRID 1778348 reaction equation
C1(S(CC2C(C(OC)=O)=C(O)C(C3C=COC=3CO)=CC=2)(=O)=O)C=CC=CC=1.[C:29]([C:32]1[O:33][CH:34]=[CH:35][C:36]=1[C:37]1[C:38]([OH:57])=[C:39]([C:44]([CH2:47][S:48]([C:51]2[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=2)(=[O:50])=[O:49])=[CH:45][CH:46]=1)[C:40]([O:42][CH3:43])=[O:41])(=[O:31])[CH3:30]>>[C:51]1([S:48]([CH2:47][C:44]2[C:39]([C:40]([O:42][CH3:43])=[O:41])=[C:38]([OH:57])[C:37]([C:36]3[CH:35]=[CH:34][O:33][C:32]=3[CH:29]([OH:31])[CH3:30])=[CH:46][CH:45]=2)(=[O:50])=[O:49])[CH:52]=[CH:53][CH:54]=[CH:55][CH:56]=1

Participants

3

Reactant 2

HCID 66685067Methyl 3-(2-acetylfuran-3-yl)-6-benzenesulfonylmethyl-2-hydroxybenzoate2×HCID 66685310Methyl 6-(benzenesulfonylmethyl)-2-hydroxy-3-(2-hydroxymethylfuran-3-yl)-benzoate

Product 1

HCID 66685568Methyl 6-(benzenesulfonylmethyl)-2-hydroxy-3-[2-(1-hydroxyethyl)-furan-3-yl]-benzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 19, starting from methyl 3-(2-acetylfuran-3-yl)-6-benzenesulfonylmethyl-2-hydroxybenzoate (Intermediate 32).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6cbe135a26974f758740dd46f10e446c
Source dataset
uspto-grants-2016_02
Patent number
US09266896B2

Reaction notes

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