3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carbaldehyde → Methyl 6-(benzenesulfonylmethyl)-3-(2-formylfuran-3-yl)-2-hydroxybenzoate

HRID 1778355Notes

Reaction equation

HRID 1778355 reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([OH:21])[C:14](Br)=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:23]([C:25]1[O:26][CH:27]=[CH:28][C:29]=1B1OC(C)(C)C(C)(C)O1)=[O:24]>>[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([OH:21])[C:14]([C:29]3[CH:28]=[CH:27][O:26][C:25]=3[CH:23]=[O:24])=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 164141993-(Tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carbaldehydeHCID 66685467Methyl 6-(benzenesulfonylmethyl)-3-bromo-2-hydroxybenzoate2×

Product 1

HCID 86684730Methyl 6-(benzenesulfonylmethyl)-3-(2-formylfuran-3-yl)-2-hydroxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 26, starting from methyl 6-(benzenesulfonylmethyl)-3-bromo-2-hydroxybenzoate (Intermediate 40) and 2-formylfuran-3-boronic acid pinacol ester

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d77a09c7fcf84aefb2eb603c54bb0acb
Source dataset
uspto-grants-2016_02
Patent number
US09266896B2

Reaction notes

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