HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-(Tert-butyldimethylsilanyloxy)-ethyl]-furan-3-yl-boronic acid → Methyl 6-amino-3-{2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-furan-3-yl}-2-hydroxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-(Tert-butyldimethylsilanyloxy)-ethyl]-furan-3-yl-boronic acid | HCID 66685795 | — |
| Reactant | Methyl 6-amino-3-bromo-2-hydroxybenzoate | HCID 66685945 | — |
| Product | Methyl 6-amino-3-{2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-furan-3-yl}-2-hydroxybenzoate | HCID 86684732 | — |
Reaction Steps
Prepared by proceeding in a similar manner to Intermediate 26, starting from methyl 6-amino-3-bromo-2-hydroxybenzoate (prepared according to Wang et al, Bioorg Med Chem Lett 2007 17 2817) and 2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-furan-3-yl-boronic acid (Intermediate 33). The material was used without further characterisation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266896B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-0ae4ed4858aa4f63a751a16a8362b829 |
| Source note | uspto-grants-2016_02 |