HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → tert-butyl N-(chlorosulfonyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | tert-butyl N-(chlorosulfonyl)carbamate | HCID 15677406 | — |
Reaction Steps
To a solution of chlorosulfonyl isocyanate (0.087 mL, 1 mmol) in CH2Cl2 (20 mL) was added tert-butanol (0.096 mL, 1 mmol) in ice-bath. The mixture was stirred at room temperature for 2 hours. A solution of N-tert-butoxycarbonylsulfamoyl chloride in CH2Cl2 (−0.05 M) was obtained, which was used for next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266904B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-596d98fc7e9745689d2547ae30a89069 |
| Source note | uspto-grants-2016_02 |