huagongshe.com
HRID1778487

反应详情

EQUATION

反应方程式

HRID 1778487 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CC2COCC(C1)N2
HCID53415349

tert-Butyl 3-oxa-7,9-diazabicyclo[3.3.1]nonane-7-carboxylate

C11H20N2O3

结构：COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl
HCID89995948

未命名化合物

结构：COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Br
HCID117706695

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COC(=O)C1=C(CN2C3CNCC2COC3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Br
HCID117706699

未命名化合物

PROCEDURE

实验过程

Compound 53b was prepared in analogy to intermediate AC in Example 15, starting from 3-oxa-7,9-diaza-bicyclo[3.3.1]nonane-7-carboxylic acid tert-butyl ester and methyl (4R)-4-(2-bromo-4-fluoro-phenyl)-6-(bromomethyl)-2-thiazol-2-yl-1,4-dihydropyrimidine-5-carboxylate 53a, while 53a was prepared in analogy to compound C in Example 1.