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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778508Generated: November 1, 2026

2-Bromo-3-fluorobenzaldehyde → HCID 131734822, compound

https://huagongshe.com/reaction/1778508

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-3-fluorobenzaldehydeHCID 24820504—
ReactantMethyl (R)-6-(bromomethyl)-4-(2-chloro-4-fluorophenyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylateHCID 89995948—
ProductHCID 131734822HCID 131734822—

Reaction Steps

Methyl (4R)-4-(2-bromo-3-fluoro-phenyl)-6-(bromomethyl)-2-thiazol-2-yl-1,4-dihydropyrimidine-5-carboxylate 94a was prepared in analogy to compound C with procedures shown in Example 1 by using 2-bromo-3-fluorobenzaldehyde instead of 2-chloro-4-fluoro-benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266904B2
Source datasetuspto-grants-2016_02
ORD IDord-5d8dcee950034a81b13fed2e6df68fe1
Source noteuspto-grants-2016_02