HCID 117697851, compound → HCID 117698123, compound

HRID 1778519Notes

Reaction equation

HRID 1778519 reaction equation
C12NC(COC1)CC1O[N:4]=[CH:3]C2=1.[OH:13][CH:14]1[C:21](=[O:22])[CH2:20][CH:19]2[N:23]([C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[CH:15]1[CH2:16][O:17][CH2:18]2>>[C:27]([O:26][C:24]([N:23]1[CH:15]2[CH2:16][O:17][CH2:18][CH:19]1[C:20]1[CH:3]=[N:4][O:22][C:21]=1[CH:14]2[OH:13])=[O:25])([CH3:30])([CH3:29])[CH3:28]

Participants

3

Reactant 2

HCID 117697851HCID 117697851, compoundHCID 117697985HCID 117697985, compound

Product 1

HCID 117698123HCID 117698123, compound

Procedure

7-Hydroxy-5,10-dioxa-4,12-diaza-tricyclo[6.3.1.0*2,6*]dodeca-2(6),3-diene-12-carboxylic acid tert-butyl ester 106d was prepared in analogy to compound 105a in Example 105, starting with 106c (260 mg). 141 mg of 106d was obtained as a colorless oil. MS: calc'd (MH+) 283, measured (MH+) 283.

Sources & evidence

ORD record
ord-772cc57615bb4521816b8d3c6f09815d
Source dataset
uspto-grants-2016_02
Patent number
US09266904B2

Reaction notes

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