Triacetoxyperiodinane → HCID 131734834, compound

Participants

Reaction Steps

A mixture of O7-benzyl O5-ethyl (5R)-2-hydroxy-7-azabicyclo[2.2.1]heptane-5,7-dicarboxylate (0.37 g, 1.1 mmol), Dess-martin reagent (1.38 g, 3.3 mmol) in DCM (50 mL) was stirred for 12 hours. After removal of solvent, the residue was purified by silica gel chromatography to give O7-benzyl O5-ethyl (5R)-2-oxo-7-azabicyclo[2.2.1]heptane-5,7-dicarboxylate 151e. Yield: 90%. MS: calc'd (MH +) 304, measured (MH +) 304.

Provenance & Evidence