Methyl 4-bromo-2-(bromomethyl)benzoate → HCID 178514906, compound

HRID 1778673Notes

Reaction equation

HRID 1778673 reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8]C)=O)=[C:4]([CH2:12]Br)[CH:3]=1.Cl.[NH2:15][C@@H:16]1[CH2:21][CH2:20][C@H:19]([OH:22])[CH2:18][CH2:17]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:10][CH:11]=1)[C:6](=[O:8])[N:15]([C@H:16]1[CH2:21][CH2:20][C@@H:19]([OH:22])[CH2:18][CH2:17]1)[CH2:12]2

Participants

3

Reactant 2

HCID 22031079Methyl 4-bromo-2-(bromomethyl)benzoateHCID 178479277HCID 178479277, compound

Product 1

HCID 178514906HCID 178514906, compound

Procedure

This compound was prepared by using procedures analogous to those described for the synthesis of Example 15, Step 1 starting from methyl 4-bromo-2-(bromomethyl)benzoate and cis-4-aminocyclohexanol hydrochloride. LCMS (M+H)+=310.0/312.0.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-6d3c76e6466348bcba8c77a9b8f17837
Source dataset
uspto-grants-2016_02
Patent number
US09266892B2

Reaction notes

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