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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778685Generated: November 1, 2026

N-Iodosuccinimide → 6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1H-pyrazolo[4,3-c]pyridine

https://huagongshe.com/reaction/1778685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-IodosuccinimideHCID 120273—
Reactant6-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridineHCID 86722816—
Product6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1H-pyrazolo[4,3-c]pyridineHCID 178493490—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 1, Step 5-6 starting from 6-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine and N-iodosuccinimide. LCMS (M+H)+=418.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-8dcc1ca82d8b44c789109c5ac72ba7ed
Source noteuspto-grants-2016_02