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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778700Generated: October 26, 2026

5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-2-benzofuran-1-one → 5-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-y]-2-benzofuran-1 (3H)-one

https://huagongshe.com/reaction/1778700

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-2-benzofuran-1-oneHCID 58074623—
Reactant6-(2,6-dichloro-3,5-dimethoxyphenyl)-3-iodo-1H-pyrazolo[4,3-c]pyridineHCID 178493454—
Product5-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-y]-2-benzofuran-1 (3H)-oneHCID 76285359—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 4, Step 2 starting from 6-(2,6-dichloro-3,5-dimethoxyphenyl)-3-iodo-1H-pyrazolo[4,3-c]pyridine and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-benzofuran-1(3H)-one. LCMS (M+H)+: 456.0/458.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-66f072d4a19b490690673f90fe610af2
Source noteuspto-grants-2016_02