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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778713Generated: October 29, 2026

4-Amino-1-methylpiperidine → 2-{4-[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-1H-pyrazol-1-yl}-N-(1-methylpiperidin-4-yl)acetamide

https://huagongshe.com/reaction/1778713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-1-methylpiperidineHCID 2737531—
Reactant{4-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-1H-pyrazol-1-yl}acetic acidHCID 86722827—
Product2-{4-[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-1H-pyrazol-1-yl}-N-(1-methylpiperidin-4-yl)acetamideHCID 76285266—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 36, Step 2, starting from {4-[6-(2,6-dichloro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-1H-pyrazol-1-yl}acetic acid and 1-methylpiperidin-4-amine. LCMS (M+H)+=544.1/546.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-ea5e39989d284ec38047ddeed8676747
Source noteuspto-grants-2016_02