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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778741Generated: October 30, 2026

HCID 86722838, compound → 3-[6-(2,6-difluoro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-6-ethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one

https://huagongshe.com/reaction/1778741

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86722838HCID 86722838—
Reactant(6-ethyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acidHCID 86722841—
Product3-[6-(2,6-difluoro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-6-ethyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-oneHCID 76284935—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 52, Step 8 starting from 6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine and (6-ethyl-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)boronic acid. LCMS (M+H)+=452.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-3646bdd29e1b40afb14029588d253b26
Source noteuspto-grants-2016_02