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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778745Generated: October 31, 2026

HCID 86722838, compound → 5-[6-(2,6-difluoro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-2-(2-methoxyethyl)isoindolin-1-one

https://huagongshe.com/reaction/1778745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86722838HCID 86722838—
ReactantHCID 86722842HCID 86722842—
Product5-[6-(2,6-difluoro-3,5-dimethoxyphenyl)-1H-pyrazolo[4,3-c]pyridin-3-yl]-2-(2-methoxyethyl)isoindolin-1-oneHCID 76284842—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 52, Step 8 starting from 6-(2,6-difluoro-3,5-dimethoxyphenyl)-3-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine and 2-(2-methoxyethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one. LCMS (M+H)+=481.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-46a013ec56684b779906dc96343cc336
Source noteuspto-grants-2016_02