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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778760Generated: November 1, 2026

N,N-Dimethylethylenediamine → 5-Bromo-2-[2-(dimethylamino)ethyl]isoindolin-1-one

https://huagongshe.com/reaction/1778760

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-DimethylethylenediamineHCID 66053—
Reactant4-Bromo-2-(bromomethyl)benzoateHCID 23158145—
Product5-Bromo-2-[2-(dimethylamino)ethyl]isoindolin-1-oneHCID 86722856—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 52, Step 6 starting from 4-bromo-2-(bromomethyl)benzoate and N,N-dimethylethylenediamine (Aldrich Cat No. D158003). LCMS (M+H)+=283.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266892B2
Source datasetuspto-grants-2016_02
ORD IDord-e1af0cc2467f4368bf4c61be1684ce40
Source noteuspto-grants-2016_02