HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalic Anhydride → HCID 86681297, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalic Anhydride | HCID 6811 | — |
| Reactant | 3-cyclopropyl-1H-pyrazol-5-amine | HCID 2758014 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86681297 | HCID 86681297 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
5-Cyclopropyl-1H-pyrazol-3-amine (5 g) was slurried in dioxane (80 mL) and N,N-dimethylformamide (80 mL), then phthalic anhydride (6 g) was added and the reaction was heated at 120° C. for 4 days. The reaction was cooled and concentrated. The crude material was triturated with isopropyl ether/ethanol 1/1 (30 mL) to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09266877B2 |
| Source dataset | uspto-grants-2016_02 |
| ORD ID | ord-99495f690449446aa073eb8414b0f29b |
| Source note | uspto-grants-2016_02 |