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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1778865Generated: November 3, 2026

Cyclohexanol → 1-Bromo-2-chloro-3-(cyclohexyloxy)benzene

https://huagongshe.com/reaction/1778865

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanolHCID 7966—
Reactantm-(Dimethylamino)benzyl alcoholHCID 90133—
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 2774010—
ReactantPhenol, bromochloro-HCID 6455237—
Product1-Bromo-2-chloro-3-(cyclohexyloxy)benzeneHCID 86681310—

Reaction Steps

The title compound was prepared by substituting for cyclohexanol for (3-(dimethylamino)phenyl)methanol and 3-bromo-2-chlorophenol for 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 34A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09266877B2
Source datasetuspto-grants-2016_02
ORD IDord-7b7a266fb2ea4129a841d2038f9a6dc1
Source noteuspto-grants-2016_02